BDBM50016737 (8-Methoxy-1,2,3,4-tetrahydro-naphthalen-2-yl)-dipropyl-amine::CHEMBL11760

SMILES CCCN(CCC)C1CCc2cccc(OC)c2C1

InChI Key InChIKey=SPOMVKJPPZWHRF-UHFFFAOYSA-N

Data  11 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 11 hits for monomerid = 50016737   

Target5-hydroxytryptamine receptor 1A(Rat)
Virginia Commonwealth University

Curated by ChEMBL
LigandPNGBDBM50016737(CHEMBL11760 | (8-Methoxy-1,2,3,4-tetrahydro-naphth...)
Affinity DataKi:  1.30nMAssay Description:Binding affinity against 5-hydroxytryptamine 1A receptor in rat hippocampal tissueMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 1A(Rat)
Virginia Commonwealth University

Curated by ChEMBL
LigandPNGBDBM50016737(CHEMBL11760 | (8-Methoxy-1,2,3,4-tetrahydro-naphth...)
Affinity DataKi:  1.30nMAssay Description:Binding affinity at [3H]8-OH-DPAT-Labeled 5-hydroxytryptamine 1A receptor sites in rat brain hippocampal membranesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 1A(Rat)
Virginia Commonwealth University

Curated by ChEMBL
LigandPNGBDBM50016737(CHEMBL11760 | (8-Methoxy-1,2,3,4-tetrahydro-naphth...)
Affinity DataKi:  1.30nMAssay Description:Displacement of [3H]-8-OH-DPAT from 5-HT1A receptor in rat hippocampal membranesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/22/2019
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 1A(Rat)
Virginia Commonwealth University

Curated by ChEMBL
LigandPNGBDBM50016737(CHEMBL11760 | (8-Methoxy-1,2,3,4-tetrahydro-naphth...)
Affinity DataKi:  2.60nMAssay Description:Binding affinity of a compound to rat brain 5-hydroxytryptamine 1A (serotonin) receptor assayed by radiolabeled [3H]-8-OH-DPAT ligand displacementMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/21/2020
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 1A(Rat)
Virginia Commonwealth University

Curated by ChEMBL
LigandPNGBDBM50016737(CHEMBL11760 | (8-Methoxy-1,2,3,4-tetrahydro-naphth...)
Affinity DataKi:  3.10nMAssay Description:Displacement of [3H]8-OH-DPAT from rat hippocampal 5-hydroxytryptamine 1A receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/17/2010
Entry Details Article

Target5-hydroxytryptamine receptor 1A(Rat)
Virginia Commonwealth University

Curated by ChEMBL
LigandPNGBDBM50016737(CHEMBL11760 | (8-Methoxy-1,2,3,4-tetrahydro-naphth...)
Affinity DataKi:  10nMAssay Description:Binding affinity against 5-hydroxytryptamine 1A receptor in homogenated rat brain tissue, using by [3H]8-OH-DPAT as radioligandMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/25/2012
Entry Details Article
PubMed
TargetD(2) dopamine receptor(Rat)
Medicinaregatan

Curated by ChEMBL
LigandPNGBDBM50016737(CHEMBL11760 | (8-Methoxy-1,2,3,4-tetrahydro-naphth...)
Affinity DataKi:  160nMAssay Description:Binding affinity against dopamine receptor D2 in homogenated rat brain tissue, using by [3H]spiperone as radioligandMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/25/2012
Entry Details Article
PubMed
TargetSerotonin 2 (5-HT2) receptor(Rat)
Virginia Commonwealth University

Curated by ChEMBL
LigandPNGBDBM50016737(CHEMBL11760 | (8-Methoxy-1,2,3,4-tetrahydro-naphth...)
Affinity DataKi:  280nMAssay Description:Binding affinity towards 5-hydroxytryptamine 2 receptor using [3H]- 1-(4-bromo-2,5-dimethoxy-phenyl)-2-aminopropane (D) as radioligandMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 1B(Rat)
Virginia Commonwealth University

Curated by ChEMBL
LigandPNGBDBM50016737(CHEMBL11760 | (8-Methoxy-1,2,3,4-tetrahydro-naphth...)
Affinity DataKi: >1.00E+3nMAssay Description:Evaluated for binding affinity towards 5-hydroxytryptamine 1B receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetSerotonin 2 (5-HT2) receptor(Rat)
Virginia Commonwealth University

Curated by ChEMBL
LigandPNGBDBM50016737(CHEMBL11760 | (8-Methoxy-1,2,3,4-tetrahydro-naphth...)
Affinity DataKi:  3.05E+3nMAssay Description:Binding affinity towards 5-hydroxytryptamine 2 receptor using [3H]- ketanserin as radioligandMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 1B(Rat)
Virginia Commonwealth University

Curated by ChEMBL
LigandPNGBDBM50016737(CHEMBL11760 | (8-Methoxy-1,2,3,4-tetrahydro-naphth...)
Affinity DataKi:  3.97E+3nMAssay Description:Binding affinity against 5-hydroxytryptamine 1B receptor in rat striatal membranes using [3H]5-HT as radioligandMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/17/2010
Entry Details Article