BDBM50016892 5-Methoxy-1,7-dimethyl-2,3,4,4a,10,10a-hexahydro-1H-9-oxa-1-aza-phenanthrene::CHEMBL162449

SMILES COc1cc(C)cc2OC[C@@H]3[C@H](CCCN3C)c12

InChI Key InChIKey=ZUULIVZIVGZUBG-UHFFFAOYSA-N

Data  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50016892   

TargetSerotonin 2 (5-HT2) receptor(Rat)
Ciba-Geigy

Curated by ChEMBL
LigandPNGBDBM50016892(CHEMBL162449 | 5-Methoxy-1,7-dimethyl-2,3,4,4a,10,...)
Affinity DataIC50: 42nMAssay Description:Concentration necessary to achieve half maximal inhibition of [3H]ketanserin binding to 5-hydroxytryptamine 2 receptor at 1 uMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 1A(Rat)
Ciba-Geigy

Curated by ChEMBL
LigandPNGBDBM50016892(CHEMBL162449 | 5-Methoxy-1,7-dimethyl-2,3,4,4a,10,...)
Affinity DataIC50: 75nMAssay Description:Concentration necessary to achieve half maximal inhibition of [3H]8-Hydroxy-2-(di-n-propylamino)tetralin binding to 5-hydroxytryptamine 1A receptor a...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 1B(Rat)
Ciba-Geigy

Curated by ChEMBL
LigandPNGBDBM50016892(CHEMBL162449 | 5-Methoxy-1,7-dimethyl-2,3,4,4a,10,...)
Affinity DataIC50: 825nMAssay Description:Concentration necessary to achieve half maximal inhibition of [125I]- Iodocyanopindolol binding to 5-hydroxytryptamine 1B receptor at 1 uMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetAlpha-2A adrenergic receptor(Bovine)
Ciba-Geigy

Curated by ChEMBL
LigandPNGBDBM50016892(CHEMBL162449 | 5-Methoxy-1,7-dimethyl-2,3,4,4a,10,...)
Affinity DataIC50: 946nMAssay Description:Concentration necessary to achieve half maximal inhibition of [3H]clonidine binding to Alpha-2 adrenergic receptor at 1 uMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed