BDBM50017059 3,4-Dibromo-N-methyl-N-(1-methyl-1-aza-spiro[4.5]dec-6-yl)-benzamide::CHEMBL279065

SMILES CN([C@H]1CCCC[C@@]11CCCN1C)C(=O)c1ccc(Br)c(Br)c1

InChI Key InChIKey=XHBTZWGPHRHWQZ-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50017059   

TargetMu-type opioid receptor(Guinea pig)
Ciba-Geigy

Curated by ChEMBL
LigandPNGBDBM50017059(CHEMBL279065 | 3,4-Dibromo-N-methyl-N-(1-methyl-1-...)
Affinity DataIC50: 2nMAssay Description:Inhibitory activity against opioid receptor mu of guinea pig brain using [3H]DAGO radioligandMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/19/2012
Entry Details Article
PubMed
TargetKappa-type opioid receptor(Guinea pig)
Ciba-Geigy

Curated by ChEMBL
LigandPNGBDBM50017059(CHEMBL279065 | 3,4-Dibromo-N-methyl-N-(1-methyl-1-...)
Affinity DataIC50: 105nMAssay Description:Binding inhibition against Opioid receptor kappa 1 of guinea pig was determined using [3H]ethylketocyclazocineMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/19/2012
Entry Details Article
PubMed
TargetDelta-type opioid receptor(Human)
Ciba-Geigy

Curated by ChEMBL
LigandPNGBDBM50017059(CHEMBL279065 | 3,4-Dibromo-N-methyl-N-(1-methyl-1-...)
Affinity DataIC50: 2.30E+3nMAssay Description:Inhibitory activity against Opioid receptor delta 1 of guinea pig was determined by using [3H]DADLE radioligandMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/19/2012
Entry Details Article
PubMed