BDBM50017342 CHEMBL1588664

SMILES OC(=O)c1cc(NC(=O)c2cccc(NC(=O)c3ccco3)c2)ccc1O

InChI Key InChIKey=HTJWLEGCECXGSQ-UHFFFAOYSA-N

Data  6 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 6 hits for monomerid = 50017342   

TargetNAD-dependent protein deacylase sirtuin-6(Human)
University of Genoa

Curated by ChEMBL
LigandPNGBDBM50017342(CHEMBL1588664)
Affinity DataIC50: 8.90E+4nMAssay Description:Inhibition of human recombinant SIRT6 assessed as reduction in NAD+-dependent deacetylase activity using Arg-His-Lys-Lys(epsilon-acetyl)-AMC substrat...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/15/2020
Entry Details Article
PubMed
TargetNAD-dependent protein deacylase sirtuin-6(Human)
University of Genoa

Curated by ChEMBL
LigandPNGBDBM50017342(CHEMBL1588664)
Affinity DataIC50: 8.90E+4nMAssay Description:Inhibition of SIRT6 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/10/2015
Entry Details Article
PubMed
TargetNAD-dependent protein deacetylase sirtuin-2(Human)
University of Genoa

Curated by ChEMBL
LigandPNGBDBM50017342(CHEMBL1588664)
Affinity DataIC50: 7.51E+5nMAssay Description:Inhibition of human recombinant SIRT2 assessed as reduction in NAD+-dependent deacetylase activity using Arg-His-Lys-Lys(epsilon-acetyl)-AMC substrat...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/15/2020
Entry Details Article
PubMed
TargetNAD-dependent protein deacetylase sirtuin-2(Human)
University of Genoa

Curated by ChEMBL
LigandPNGBDBM50017342(CHEMBL1588664)
Affinity DataIC50: 7.51E+5nMAssay Description:Inhibition of SIRT2 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/10/2015
Entry Details Article
PubMed
TargetNAD-dependent protein deacetylase sirtuin-1(Human)
University of Bologna

Curated by ChEMBL
LigandPNGBDBM50017342(CHEMBL1588664)
Affinity DataIC50: 1.58E+6nMAssay Description:Inhibition of SIRT1 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/10/2015
Entry Details Article
PubMed
TargetNAD-dependent protein deacetylase sirtuin-1(Human)
University of Bologna

Curated by ChEMBL
LigandPNGBDBM50017342(CHEMBL1588664)
Affinity DataIC50: 1.58E+6nMAssay Description:Inhibition of human recombinant SIRT1 assessed as reduction in NAD+-dependent deacetylase activity using Arg-His-Lys-Lys(epsilon-acetyl)-AMC substrat...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/15/2020
Entry Details Article
PubMed