BDBM50017350 CHEMBL3288281::US20250213569, Compound 112

SMILES ON1C(=O)C(C(=O)NCc2ccc(F)cc2)c2ccc(cc2C1=O)C(F)(F)F

InChI Key InChIKey=KUJQXKRJIMBEPJ-UHFFFAOYSA-N

Data  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50017350   

TargetIntegrase(Human immunodeficiency virus type 1)
University of Lille

Curated by ChEMBL
LigandPNGBDBM50017350(CHEMBL3288281 | US20250213569, Compound 112)
Affinity DataIC50: 20nMAssay Description:Inhibition of HIV-1 overall integrase activity using 5'-digoxigenin-labeled GACCCTTTTAGTCAGTGTGGAAAATCTCTAGCAGT-3' as substrate after 1 hr by ELISAMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/10/2015
Entry Details Article
PubMed
TargetReplicase polyprotein 1ab(2019-nCoV)
New York University

US Patent
LigandPNGBDBM50017350(CHEMBL3288281 | US20250213569, Compound 112)
Affinity DataIC50: 1.94E+4nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/22/2025
Entry Details
Go to US Patent

TargetReplicase polyprotein 1ab(SARS-CoV)
New York University

US Patent
LigandPNGBDBM50017350(CHEMBL3288281 | US20250213569, Compound 112)
Affinity DataIC50: 4.22E+3nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/22/2025
Entry Details
Go to US Patent

TargetReplicase polyprotein 1a(MERS-CoV)
New York University

US Patent
LigandPNGBDBM50017350(CHEMBL3288281 | US20250213569, Compound 112)
Affinity DataIC50: 4.39E+3nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/22/2025
Entry Details
Go to US Patent