BDBM50017367 CHEMBL3288276

SMILES ON1C(=O)C(C(=O)NCc2ccc(F)cc2)c2ccc(F)cc2C1=O

InChI Key InChIKey=BUZMGWVENCPVAN-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50017367   

TargetIntegrase(Human immunodeficiency virus type 1)
University of Lille

Curated by ChEMBL
LigandPNGBDBM50017367(CHEMBL3288276 | US20250213569, Compound 111)
Affinity DataIC50: 240nMAssay Description:Inhibition of HIV-1 overall integrase activity using 5'-digoxigenin-labeled GACCCTTTTAGTCAGTGTGGAAAATCTCTAGCAGT-3' as substrate after 1 hr by ELISAMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/10/2015
Entry Details Article
PubMed
TargetReplicase polyprotein 1ab(2019-nCoV)
New York University

US Patent
LigandPNGBDBM50017367(CHEMBL3288276 | US20250213569, Compound 111)
Affinity DataIC50: 4.14E+4nMAssay Description:Commercially available 2-Hydroxyisoquinoline-1,3(2H,4H)-dione (CAS No: 6890-08-0), a well-known scaffold backbone used to develop human immunodeficie...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/22/2025
Entry Details
US Patent