BDBM50017431 4-{4-[4-(6-chloro-2-pyrazinyl)hexahydro-1-pyrazinyl]butyl}-5-sulfo-4-azatetracyclo[5.3.2.02,6.08,10]dodec-11-en-3-one; Hydrochloride::CHEMBL552874

SMILES Clc1cncc(n1)N1CCN(CCCCN2C(=O)C3C(C4C=CC3C3CC43)S2(=O)=O)CC1

InChI Key InChIKey=JNAQYZUMZHXNRY-UHFFFAOYSA-N

Data  2 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50017431   

Target5-hydroxytryptamine receptor 1A(Rat)
Wyeth-Ayerst Research

Curated by ChEMBL
LigandPNGBDBM50017431(CHEMBL552874 | 4-{4-[4-(6-chloro-2-pyrazinyl)hexah...)
Affinity DataKi:  14nMAssay Description:In vitro ability to inhibit [3H]8-OH-DPAT binding to 5-hydroxytryptamine 1A receptor of rat hippocampus (94%CI) from 12 to 17More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/18/2012
Entry Details Article
PubMed
TargetD(2) dopamine receptor(Rat)
Wyeth-Ayerst Research

Curated by ChEMBL
LigandPNGBDBM50017431(CHEMBL552874 | 4-{4-[4-(6-chloro-2-pyrazinyl)hexah...)
Affinity DataKi:  1.03E+3nMAssay Description:In vitro ability to inhibit [3H]spiperone binding to Dopamine receptor D2 of rat limbic structures and the value ranges from 116 - 159.More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/18/2012
Entry Details Article
PubMed