BDBM50017432 4-{4-[4-(2-pyrimidinyl)hexahydro-1-pyrazinyl]butyl}-5-sulfo-4-azatetracyclo[5.4.2.02,6.08,11]trideca-9,12-dien-3-one; diHydrochloride::CHEMBL3216636

SMILES O=C1C2C(C3C=CC2C2C=CC32)S(=O)(=O)N1CCCCN1CCN(CC1)c1ncccn1

InChI Key InChIKey=YPPGECIVBJQAPM-UHFFFAOYSA-N

Data  3 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50017432   

Target5-hydroxytryptamine receptor 1A(Rat)
Wyeth-Ayerst Research

Curated by ChEMBL
LigandPNGBDBM50017432(4-{4-[4-(2-pyrimidinyl)hexahydro-1-pyrazinyl]butyl...)
Affinity DataKi:  10nMAssay Description:In vitro ability to inhibit [3H]8-OH-DPAT binding to 5-HT1A receptor of rat hippocampus and the value ranges from 9 - 12More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/18/2012
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 1A(Rat)
Wyeth-Ayerst Research

Curated by ChEMBL
LigandPNGBDBM50017432(4-{4-[4-(2-pyrimidinyl)hexahydro-1-pyrazinyl]butyl...)
Affinity DataKi:  10nMAssay Description:In vitro ability to inhibit [3H]8-OH-DPAT binding to 5-HT1A receptor of rat hippocampus and the value ranges from 9 - 12More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/18/2012
Entry Details Article
PubMed
TargetD(2) dopamine receptor(Rat)
Wyeth-Ayerst Research

Curated by ChEMBL
LigandPNGBDBM50017432(4-{4-[4-(2-pyrimidinyl)hexahydro-1-pyrazinyl]butyl...)
Affinity DataKi:  136nMAssay Description:In vitro ability to inhibit [3H]spiperone binding to Dopamine receptor D2 of rat limbic structures and the value ranges from 116 - 159.More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/18/2012
Entry Details Article
PubMed