BDBM50017981 2-[4-(2,6-Dioxo-1,3-dipropyl-2,3,6,7-tetrahydro-1H-purin-8-yl)-phenoxy]-N-{2-[3-(4-isothiocyanato-phenyl)-thioureido]-ethyl}-acetamide::CHEMBL275635

SMILES CCCn1c2nc([nH]c2c(=O)n(CCC)c1=O)-c1ccc(OCC(=O)NCCNC(=S)Nc2ccc(cc2)N=C=S)cc1

InChI Key InChIKey=VPDIZCBBZYUENG-UHFFFAOYSA-N

Data  3 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50017981   

TargetAdenosine receptor A1(Bovine)
Niddk

Curated by ChEMBL
LigandPNGBDBM50017981(CHEMBL275635 | 2-[4-(2,6-Dioxo-1,3-dipropyl-2,3,6,...)
Affinity DataKi:  1.30nMAssay Description:Affinity for Adenosine A1 receptor using [3H]-N6 -(phenylisopropyl)-adenosine (R)-[3H]-PIA in rat brainMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/18/2012
Entry Details Article
PubMed
TargetAdenosine receptor A1(Rat)
Niddk

Curated by ChEMBL
LigandPNGBDBM50017981(CHEMBL275635 | 2-[4-(2,6-Dioxo-1,3-dipropyl-2,3,6,...)
Affinity DataKi:  6.60nMAssay Description:Affinity for adenosine A1 receptor using [3H]N6-(phenylisopropyl)adenosine (R)-[3H]-PIA as a radioligand in rat brain.More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/18/2012
Entry Details Article
PubMed
TargetAdenosine receptor A2a/A2b(Rat)
Niddk

Curated by ChEMBL
LigandPNGBDBM50017981(CHEMBL275635 | 2-[4-(2,6-Dioxo-1,3-dipropyl-2,3,6,...)
Affinity DataKi:  321nMAssay Description:Inhibition of [3H]N-ethyladenosine-5'-uronamide binding to Adenosine A2 receptor of rat striatal membraneMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/18/2012
Entry Details Article
PubMed