BDBM50017991 7-(2-{2-[4-(2,6-Dioxo-1,3-dipropyl-2,3,6,7-tetrahydro-1H-purin-8-yl)-phenoxy]-acetylamino}-ethylcarbamoyl)-heptanoic acid 2,5-dioxo-pyrrolidin-1-yl ester::CHEMBL8969

SMILES CCCn1c2nc([nH]c2c(=O)n(CCC)c1=O)-c1ccc(OCC(=O)NCCNC(=O)CCCCCCC(=O)ON2C(=O)CCC2=O)cc1

InChI Key InChIKey=WLCXTJZFBVFWHJ-UHFFFAOYSA-N

Data  5 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 50017991   

TargetAdenosine receptor A1(Rat)
Niddk

Curated by ChEMBL
LigandPNGBDBM50017991(CHEMBL8969 | 7-(2-{2-[4-(2,6-Dioxo-1,3-dipropyl-2,...)
Affinity DataKi:  3.70nMAssay Description:Affinity for adenosine A1 receptor using [3H]N6-(phenylisopropyl)adenosine (R)-[3H]-PIA as a radioligand in rat brain.More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/18/2012
Entry Details Article
PubMed
TargetAdenosine receptor A1(Rat)
Niddk

Curated by ChEMBL
LigandPNGBDBM50017991(CHEMBL8969 | 7-(2-{2-[4-(2,6-Dioxo-1,3-dipropyl-2,...)
Affinity DataKi:  3.70nMAssay Description:Inhibition of 1 nM [3H]N-6-(phenylisopropyl)adenosine binding to A1 receptors in rat cortical membranesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/19/2012
Entry Details Article
PubMed
TargetAdenosine receptor A1(Bovine)
Niddk

Curated by ChEMBL
LigandPNGBDBM50017991(CHEMBL8969 | 7-(2-{2-[4-(2,6-Dioxo-1,3-dipropyl-2,...)
Affinity DataKi:  23nMAssay Description:Affinity for Adenosine A1 receptor using [3H]-N6 -(phenylisopropyl)-adenosine (R)-[3H]-PIA in rat brainMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/18/2012
Entry Details Article
PubMed
TargetAdenosine receptor A2a/A2b(Rat)
Niddk

Curated by ChEMBL
LigandPNGBDBM50017991(CHEMBL8969 | 7-(2-{2-[4-(2,6-Dioxo-1,3-dipropyl-2,...)
Affinity DataKi:  207nMAssay Description:Inhibition of [3H]N-ethyladenosine-5'-uronamide binding to Adenosine A2 receptor of rat striatal membraneMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/18/2012
Entry Details Article
PubMed
TargetAdenosine receptor A2a/A2b(Rat)
Niddk

Curated by ChEMBL
LigandPNGBDBM50017991(CHEMBL8969 | 7-(2-{2-[4-(2,6-Dioxo-1,3-dipropyl-2,...)
Affinity DataKi:  207nMAssay Description:Inhibition of binding of [3H]5'-(N-ethylcarbamoyl)-adenosine to adenosine A2 receptor in rat striatal membranesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/19/2012
Entry Details Article
PubMed