BDBM50018621 6-(4-Imidazol-1-yl-phenyl)-4-methyl-4,5-dihydro-2H-pyridazin-3-one::CHEMBL31762

SMILES CC1CC(=NNC1=O)c1ccc(cc1)-n1ccnc1

InChI Key InChIKey=FJSIMGWFNGHVSV-UHFFFAOYSA-N

Data  5 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 50018621   

TargetcGMP-inhibited 3',5'-cyclic phosphodiesterase 3A/3B(Human)
Warner-Lambert

Curated by ChEMBL
LigandPNGBDBM50018621(CHEMBL31762 | 6-(4-Imidazol-1-yl-phenyl)-4-methyl-...)
Affinity DataIC50: 4.30E+4nMAssay Description:Inhibitory concentration against cAMP PDE III enzyme in guinea pigMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetcGMP-dependent 3',5'-cyclic phosphodiesterase(Human)
Warner-Lambert

Curated by ChEMBL
LigandPNGBDBM50018621(CHEMBL31762 | 6-(4-Imidazol-1-yl-phenyl)-4-methyl-...)
Affinity DataIC50: 2.60E+5nMAssay Description:Inhibition of PDE II enzyme in guinea pigMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetcGMP-dependent 3',5'-cyclic phosphodiesterase(Human)
Warner-Lambert

Curated by ChEMBL
LigandPNGBDBM50018621(CHEMBL31762 | 6-(4-Imidazol-1-yl-phenyl)-4-methyl-...)
Affinity DataIC50: 2.80E+5nMAssay Description:Inhibitory concentration against cGMP PDE II enzyme in guinea pigMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
LigandPNGBDBM50018621(CHEMBL31762 | 6-(4-Imidazol-1-yl-phenyl)-4-methyl-...)
Affinity DataIC50: 1.00E+6nMAssay Description:Inhibitory concentration against cGMP PDE I enzyme in guinea pigMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
LigandPNGBDBM50018621(CHEMBL31762 | 6-(4-Imidazol-1-yl-phenyl)-4-methyl-...)
Affinity DataIC50: 1.00E+6nMAssay Description:Inhibitory concentration against cAMP PDE I enzyme in guinea pigMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed