BDBM50018623 6-[4-(4-Hydroxymethyl-imidazol-1-yl)-phenyl]-4,5-dihydro-2H-pyridazin-3-one::CHEMBL286502

SMILES OCc1cn(cn1)-c1ccc(cc1)C1=NNC(=O)CC1

InChI Key InChIKey=BCKUYFGVMIQCMI-UHFFFAOYSA-N

Data  5 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 50018623   

TargetcGMP-inhibited 3',5'-cyclic phosphodiesterase 3A/3B(Human)
Warner-Lambert

Curated by ChEMBL
LigandPNGBDBM50018623(CHEMBL286502 | 6-[4-(4-Hydroxymethyl-imidazol-1-yl...)
Affinity DataIC50: 4.10E+3nMAssay Description:Inhibitory concentration against cAMP PDE III enzyme in guinea pigMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetcGMP-dependent 3',5'-cyclic phosphodiesterase(Human)
Warner-Lambert

Curated by ChEMBL
LigandPNGBDBM50018623(CHEMBL286502 | 6-[4-(4-Hydroxymethyl-imidazol-1-yl...)
Affinity DataIC50: 3.50E+5nMAssay Description:Inhibitory concentration against cGMP PDE II enzyme in guinea pigMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetcGMP-dependent 3',5'-cyclic phosphodiesterase(Human)
Warner-Lambert

Curated by ChEMBL
LigandPNGBDBM50018623(CHEMBL286502 | 6-[4-(4-Hydroxymethyl-imidazol-1-yl...)
Affinity DataIC50: 3.50E+5nMAssay Description:Inhibitory concentration against cAMP PDE II enzyme in guinea pigMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
LigandPNGBDBM50018623(CHEMBL286502 | 6-[4-(4-Hydroxymethyl-imidazol-1-yl...)
Affinity DataIC50: 1.00E+6nMAssay Description:Inhibitory concentration against cGMP PDE I enzyme in guinea pigMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
LigandPNGBDBM50018623(CHEMBL286502 | 6-[4-(4-Hydroxymethyl-imidazol-1-yl...)
Affinity DataIC50: 1.00E+6nMAssay Description:Inhibitory concentration against cAMP PDE I enzyme in guinea pigMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed