BDBM50018624 6-[4-(4,5,6,7-Tetrahydro-benzoimidazol-1-yl)-phenyl]-4,5-dihydro-2H-pyridazin-3-one::CHEMBL30623

SMILES O=C1CCC(=NN1)c1ccc(cc1)-n1cnc2CCCCc12

InChI Key InChIKey=VBGDSOIMEGVCIK-UHFFFAOYSA-N

Data  5 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 50018624   

TargetcGMP-inhibited 3',5'-cyclic phosphodiesterase 3A/3B(Human)
Warner-Lambert

Curated by ChEMBL
LigandPNGBDBM50018624(CHEMBL30623 | 6-[4-(4,5,6,7-Tetrahydro-benzoimidaz...)
Affinity DataIC50: 1.10E+3nMAssay Description:Inhibitory concentration against cAMP PDE III enzyme in guinea pigMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetcGMP-dependent 3',5'-cyclic phosphodiesterase(Human)
Warner-Lambert

Curated by ChEMBL
LigandPNGBDBM50018624(CHEMBL30623 | 6-[4-(4,5,6,7-Tetrahydro-benzoimidaz...)
Affinity DataIC50: 4.90E+4nMAssay Description:Inhibitory concentration against cAMP PDE II enzyme in guinea pigMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetcGMP-dependent 3',5'-cyclic phosphodiesterase(Human)
Warner-Lambert

Curated by ChEMBL
LigandPNGBDBM50018624(CHEMBL30623 | 6-[4-(4,5,6,7-Tetrahydro-benzoimidaz...)
Affinity DataIC50: 4.90E+4nMAssay Description:Inhibitory concentration against cAMP PDE II enzyme in guinea pigMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
LigandPNGBDBM50018624(CHEMBL30623 | 6-[4-(4,5,6,7-Tetrahydro-benzoimidaz...)
Affinity DataIC50: 1.40E+5nMAssay Description:Inhibitory concentration against cGMP PDE I enzyme in guinea pigMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
LigandPNGBDBM50018624(CHEMBL30623 | 6-[4-(4,5,6,7-Tetrahydro-benzoimidaz...)
Affinity DataIC50: 1.80E+5nMAssay Description:Inhibitory concentration against cAMP PDE I enzyme in guinea pigMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed