BDBM50018627 5-(4-Imidazol-1-yl-phenyl)-6-methyl-2-oxo-1,2,3,4-tetrahydro-pyridine-3-carbonitrile::CHEMBL61692

SMILES CC1=C(CC(C#N)C(=O)N1)c1ccc(cc1)-n1ccnc1

InChI Key InChIKey=UEMLUAWBMUYPGO-UHFFFAOYSA-N

Data  5 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 50018627   

TargetcGMP-inhibited 3',5'-cyclic phosphodiesterase 3A/3B(Human)
Warner-Lambert

Curated by ChEMBL
LigandPNGBDBM50018627(CHEMBL61692 | 5-(4-Imidazol-1-yl-phenyl)-6-methyl-...)
Affinity DataIC50: 1.90E+3nMAssay Description:Inhibition of cAMP PDE III enzymeMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/15/2012
Entry Details Article
PubMed
LigandPNGBDBM50018627(CHEMBL61692 | 5-(4-Imidazol-1-yl-phenyl)-6-methyl-...)
Affinity DataIC50: 3.90E+4nMAssay Description:Inhibition of cAMP PDE I enzymeMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/15/2012
Entry Details Article
PubMed
TargetcGMP-dependent 3',5'-cyclic phosphodiesterase(Human)
Warner-Lambert

Curated by ChEMBL
LigandPNGBDBM50018627(CHEMBL61692 | 5-(4-Imidazol-1-yl-phenyl)-6-methyl-...)
Affinity DataIC50: 4.30E+4nMAssay Description:Inhibition of cAMP PDE II enzymeMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/15/2012
Entry Details Article
PubMed
TargetcGMP-dependent 3',5'-cyclic phosphodiesterase(Human)
Warner-Lambert

Curated by ChEMBL
LigandPNGBDBM50018627(CHEMBL61692 | 5-(4-Imidazol-1-yl-phenyl)-6-methyl-...)
Affinity DataIC50: 1.20E+5nMAssay Description:Inhibition of cGMP PDE II enzymeMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/15/2012
Entry Details Article
PubMed
LigandPNGBDBM50018627(CHEMBL61692 | 5-(4-Imidazol-1-yl-phenyl)-6-methyl-...)
Affinity DataIC50: 1.30E+5nMAssay Description:Inhibition cGMP PDE I enzymeMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/15/2012
Entry Details Article
PubMed