BDBM50018632 12-[2-Amino-3-(4-hydroxy-phenyl)-propionylamino]-2-benzyl-3,7,13-trioxo-1,4,8triaza-cyclotridecane-5-carboxylic acid amide::CHEMBL63972

SMILES N[C@@H](Cc1ccc(O)cc1)C(=O)N[C@@H]1CCCNC(=O)C[C@H](NC(=O)[C@@H](Cc2ccccc2)NC1=O)C(N)=O

InChI Key InChIKey=HNDAPGXWFDLKOJ-UHFFFAOYSA-N

Data  2 KI  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50018632   

TargetMu-type opioid receptor(Rat)
Clinical Research Institute of Montreal

Curated by ChEMBL
LigandPNGBDBM50018632(CHEMBL63972 | 12-[2-Amino-3-(4-hydroxy-phenyl)-pro...)
Affinity DataKi:  3.04E+3nMAssay Description:Binding affinity towards Opioid receptor mu 1 in rat brain membrane using [3H]DAGO as radioligandMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetDelta-type opioid receptor(Mouse)
Clinical Research Institute of Montreal

Curated by ChEMBL
LigandPNGBDBM50018632(CHEMBL63972 | 12-[2-Amino-3-(4-hydroxy-phenyl)-pro...)
Affinity DataIC50: 8.64E+3nMAssay Description:Inhibitory activity towards electrically induced contractions in mouse vas deferens expressing delta opioid receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetMu-type opioid receptor(Guinea pig)
Clinical Research Institute of Montreal

Curated by ChEMBL
LigandPNGBDBM50018632(CHEMBL63972 | 12-[2-Amino-3-(4-hydroxy-phenyl)-pro...)
Affinity DataIC50: 2.10E+4nMAssay Description:Inhibitory activity towards electrically induced contractions in guinea pig ileum expressing Opioid receptor mu 1More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetDelta-type opioid receptor(Rat)
Clinical Research Institute of Montreal

Curated by ChEMBL
LigandPNGBDBM50018632(CHEMBL63972 | 12-[2-Amino-3-(4-hydroxy-phenyl)-pro...)
Affinity DataKi: >3.80E+5nMAssay Description:Inhibition of [3H]DSLET binding to rat brain membrane Opioid receptor delta 1More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed