BDBM50018740 4,7,8,9,10,10a-Hexahydro-5H-thiazolo[4,5-a]quinolizin-2-ylamine::CHEMBL160388

SMILES Nc1nc2C3CCCCN3CCc2s1

InChI Key InChIKey=XBPQBUKYWUVAEY-UHFFFAOYSA-N

Data  4 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50018740   

TargetAlpha-2A adrenergic receptor(Bovine)
Merck Sharp & Dohme Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50018740(CHEMBL160388 | 4,7,8,9,10,10a-Hexahydro-5H-thiazol...)
Affinity DataKi:  347nMAssay Description:Compound was evaluated for log 1/Ki at alpha-2 adrenergic receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetAlpha-2A adrenergic receptor(Bovine)
Merck Sharp & Dohme Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50018740(CHEMBL160388 | 4,7,8,9,10,10a-Hexahydro-5H-thiazol...)
Affinity DataKi:  350nMAssay Description:Affinity to alpha-2 adrenergic receptor by the displacement of [3H]clonidine from calf cerebral cortex membranesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetAlpha-1A adrenergic receptor(Bovine)
Merck Sharp & Dohme Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50018740(CHEMBL160388 | 4,7,8,9,10,10a-Hexahydro-5H-thiazol...)
Affinity DataKi:  2.80E+3nMAssay Description:Affinity to alpha-1 adrenergic receptor by the displacement of [3H]-prazosin from calf cerebral cortex membranesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetAlpha-1A adrenergic receptor(Bovine)
Merck Sharp & Dohme Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50018740(CHEMBL160388 | 4,7,8,9,10,10a-Hexahydro-5H-thiazol...)
Affinity DataKi:  2.82E+3nMAssay Description:Compound was evaluated for log 1/Ki at alpha-1 adrenergic receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed