BDBM50018798 CHEMBL3291342

SMILES [H][C@@]12CC[C@@](C)(c3c1c(=O)n(-c1ccccc1F)n3C(C)C)C2(C)C

InChI Key InChIKey=CJOCRBWZBNENBF-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50018798   

Target11-beta-hydroxysteroid dehydrogenase 1(Human)
Hoffmann-La Roche

Curated by ChEMBL
LigandPNGBDBM50018798(CHEMBL3291342)
Affinity DataIC50: 13nMAssay Description:Inhibition of full-length human 11betaHSD1 expressed in HEK293 cells assessed as cortisol level by competitive ELISAMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/11/2015
Entry Details Article
PubMed
Target11-beta-hydroxysteroid dehydrogenase 1(Rat)
Hoffmann-La Roche

Curated by ChEMBL
LigandPNGBDBM50018798(CHEMBL3291342)
Affinity DataIC50: 22nMAssay Description:Inhibition of rat 11betaHSD1 assessed as reduction of cortisone to cortisol by ELISAMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/11/2015
Entry Details Article
PubMed