BDBM50019095 1-Allyl-3-(3-hydroxy-phenyl)-2-methyl-piperidine-3-carboxylic acid ethyl ester::CHEMBL300357

SMILES CCOC(=O)[C@@]1(CCCN(CC=C)[C@H]1C)c1cccc(O)c1

InChI Key InChIKey=KUCSPWIXGVGRJJ-UHFFFAOYSA-N

Data  3 Kd

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50019095   

TargetKappa-type opioid receptor(Guinea pig)
Sri International

Curated by ChEMBL
LigandPNGBDBM50019095(CHEMBL300357 | 1-Allyl-3-(3-hydroxy-phenyl)-2-meth...)
Affinity DataKd:  830nMAssay Description:Binding affinity at Opioid receptor kappa 1 in guinea pig brain membrane determined by using [3H]U-69593 as radioligandMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/16/2012
Entry Details Article
PubMed
TargetMu-type opioid receptor(Rat)
Sri International

Curated by ChEMBL
LigandPNGBDBM50019095(CHEMBL300357 | 1-Allyl-3-(3-hydroxy-phenyl)-2-meth...)
Affinity DataKd:  310nMAssay Description:Binding affinity at Opioid receptor mu 1 in rat brain membrane was determined by using curve-fitting ligands ([3H]DHM, [3H]DADL, [3H]DSLET, [3H]EKC)More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/16/2012
Entry Details Article
PubMed
TargetDelta-type opioid receptor(Rat)
Sri International

Curated by ChEMBL
LigandPNGBDBM50019095(CHEMBL300357 | 1-Allyl-3-(3-hydroxy-phenyl)-2-meth...)
Affinity DataKd:  770nMAssay Description:Binding affinity at Opioid receptor delta 1 in rat brain membrane was determined by using curve -fitting LIGAND([3H]DHM, [3H]DADL, [3H]DSLET, [3H]EKC...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/16/2012
Entry Details Article
PubMed