BDBM50019278 4-Chloro-N-[5-(2-fluoro-phenyl)-1-methyl-2-oxo-4-oxy-2,3-dihydro-1H-benzo[e][1,4]diazepin-3-yl]-benzamide: 0.05CHCl3::CHEMBL302825

SMILES CN1c2ccccc2C(c2ccccc2F)=[N+]([O-])C(NC(=O)c2ccc(Cl)cc2)C1=O

InChI Key InChIKey=JIYPVUALLSAUFC-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50019278   

TargetCholecystokinin receptor type A(Rat)
Merck Sharp & Dohme Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50019278(CHEMBL302825 | 4-Chloro-N-[5-(2-fluoro-phenyl)-1-m...)
Affinity DataIC50: 66nMAssay Description:Half-maximal inhibition of [125I]CCK-33 binding to cholecystokinin A receptor from rat pancreatic tissueMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/16/2012
Entry Details Article
PubMed
TargetGastrin/cholecystokinin type B receptor(Human)
Merck Sharp & Dohme Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50019278(CHEMBL302825 | 4-Chloro-N-[5-(2-fluoro-phenyl)-1-m...)
Affinity DataIC50: 2.40E+3nMAssay Description:Half-maximal inhibition of [125I]gastrin binding to guinea pig gastric glandsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/16/2012
Entry Details Article
PubMed
TargetCholecystokinin receptor type A/Gastrin/cholecystokinin type B receptor(Human)
Merck Sharp & Dohme Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50019278(CHEMBL302825 | 4-Chloro-N-[5-(2-fluoro-phenyl)-1-m...)
Affinity DataIC50: 1.80E+4nMAssay Description:Half-maximal inhibition of [125I]-CCK-8(+) binding to cholecystokinin receptor from guinea pig brain tissueMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/16/2012
Entry Details Article
PubMed