BDBM50019495 CHEMBL3290734

SMILES Cc1c(\C=C\C(=O)NCC(O)=O)oc2ccc(Cl)c(C(=O)Oc3ccncc3C(=O)N3CCN(C4CC4)c4ccccc34)c12

InChI Key InChIKey=BYPOYJAQQHIBLX-UHFFFAOYSA-N

Data  2 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50019495   

TargetG-protein coupled bile acid receptor 1(Mouse)
Chinese Academy of Sciences

Curated by ChEMBL
LigandPNGBDBM50019495(CHEMBL3290734)
Affinity DataEC50:  13nMAssay Description:Agonist activity at mouse TGR5 expressed in HEK293 cells co-expressing CRE after 5.5 hrs by luciferase reporter gene assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/11/2015
Entry Details Article
PubMed
TargetG-protein coupled bile acid receptor 1(Human)
Chinese Academy of Sciences

Curated by ChEMBL
LigandPNGBDBM50019495(CHEMBL3290734)
Affinity DataEC50:  34nMAssay Description:Agonist activity at human TGR5 expressed in HEK293 cells co-expressing CRE after 5.5 hrs by luciferase reporter gene assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/11/2015
Entry Details Article
PubMed