BDBM50019683 11-Oxo-11H-pyrido[2,1-b]quinazoline-8-carboxylic acid (4-pyridin-3-yl-butyl)-amide::CHEMBL60625

SMILES O=C(NCCCCc1cccnc1)c1ccc2nc3ccccc3c(=O)n2c1

InChI Key InChIKey=LTXALSZKGGRIKD-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50019683   

TargetPlatelet-activating factor receptor(Human)
Hoffmann-La Roche

Curated by ChEMBL
LigandPNGBDBM50019683(CHEMBL60625 | 11-Oxo-11H-pyrido[2,1-b]quinazoline-...)
Affinity DataIC50: 1.80E+3nMAssay Description:Ability to inhibit platelet activating factor (PAF) binding to platelets by 50% was determined by using [3H]PAF as radioligandMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetThromboxane-A synthase(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50019683(CHEMBL60625 | 11-Oxo-11H-pyrido[2,1-b]quinazoline-...)
Affinity DataIC50: 20nMAssay Description:Inhibition of human platelet thromboxane synthase (TXA2) was determined in human plateletsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/15/2012
Entry Details Article
PubMed