BDBM50019905 CHEMBL3287210::US9533999, ii-4

SMILES CC(N1C(=O)CSc2cccnc12)c1cccc(c1)C(F)(F)F

InChI Key InChIKey=LRPBZJNZJSRNQB-UHFFFAOYSA-N

Data  2 IC50

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50019905   

TargetIntermediate conductance calcium-activated potassium channel protein 4(Human)
Temple University

Curated by ChEMBL

LigandBDBM50019905(CHEMBL3287210 | US9533999, ii-4)Copy SMILESCopy InChI

Affinity DataIC50: 41nMAssay Description:Inhibition of human KCa3.1 overexpressed in HEK293 cells assessed as thallium influx preincubated for 15 mins followed by thallium/ionomycin addition...More data for this Ligand-Target Pair

Target InfoPDBKEGG
UniProtKB/SwissProt
GoogleScholar

Ligand InfoCHEMBLPC cidPC sidSimilars

In Depth
Date in BDB:
2/11/2015
Entry Details Article
Copy Entry DOIPubMed
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TargetIntermediate conductance calcium-activated potassium channel protein 4(Human)
Temple University

Curated by ChEMBL

LigandBDBM50019905(CHEMBL3287210 | US9533999, ii-4)Copy SMILESCopy InChI

Affinity DataIC50: 41nMAssay Description:HEK293 cells over-expressing human KCa3.1 are used to measure the effects of compounds in inhibiting the KCa3.1 channel function. The assay is based ...More data for this Ligand-Target Pair

Target InfoPDBKEGG
UniProtKB/SwissProt
GoogleScholar

Ligand InfoCHEMBLPC cidPC sidSimilars

In Depth
Date in BDB:
8/7/2018
Entry Details
Copy Entry DOIGo to US Patent

Copy Rxn URL