BDBM50019950 1-(4-Fluoro-phenyl)-4-(4-phenyl-piperidin-1-yl)-butan-1-one::CHEMBL56843

SMILES Fc1ccc(cc1)C(=O)CCCN1CCC(CC1)c1ccccc1

InChI Key InChIKey=GOPOBAVSYNADGN-UHFFFAOYSA-N

Data  2 KI  3 IC50  2 Kd

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 7 hits for monomerid = 50019950   

TargetD(2) dopamine receptor(Rat)
Istituto Superiore Di Sanit£

Curated by ChEMBL
LigandPNGBDBM50019950(CHEMBL56843 | 1-(4-Fluoro-phenyl)-4-(4-phenyl-pipe...)
Affinity DataIC50: 70nMAssay Description:Ability to inhibit the specific binding of [3H]- spiroperidol to Dopamine receptor D2 in rat striatal membrane preparation by 50%More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/15/2012
Entry Details Article
PubMed
TargetD(1A) dopamine receptor(Rat)
Istituto Superiore Di Sanit£

Curated by ChEMBL
LigandPNGBDBM50019950(CHEMBL56843 | 1-(4-Fluoro-phenyl)-4-(4-phenyl-pipe...)
Affinity DataIC50: 7.50E+3nMAssay Description:Inhibitory concentration against rat striatal dopamine (D1) sensitive adenylate cyclase activityMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/15/2012
Entry Details Article
PubMed
LigandPNGBDBM50019950(CHEMBL56843 | 1-(4-Fluoro-phenyl)-4-(4-phenyl-pipe...)
Affinity DataIC50: 1.00E+4nMAssay Description:Ability to inhibit the specific binding of [3H]- dihydromorphine to opiate receptors in rat brain membrane preparation by 50%More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/15/2012
Entry Details Article
PubMed
TargetD(2) dopamine receptor(Human)
University of Nottingham

Curated by ChEMBL
LigandPNGBDBM50019950(CHEMBL56843 | 1-(4-Fluoro-phenyl)-4-(4-phenyl-pipe...)
Affinity DataKd:  7.90nMAssay Description:Displacement of PPHT-red from SNAP-tagged human D2LR expressed in CHOK1 cell membranes by TR-FRET assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/26/2021
Entry Details Article
PubMed
TargetD(2) dopamine receptor(Human)
University of Nottingham

Curated by ChEMBL
LigandPNGBDBM50019950(CHEMBL56843 | 1-(4-Fluoro-phenyl)-4-(4-phenyl-pipe...)
Affinity DataKd:  7.90nMAssay Description:Displacement of PPHT-red from SNAP-tagged human D2LR expressed in CHOK1 cell membranes by TR-FRET assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/26/2021
Entry Details Article
PubMed
TargetD(2) dopamine receptor(Human)
University of Nottingham

Curated by ChEMBL
LigandPNGBDBM50019950(CHEMBL56843 | 1-(4-Fluoro-phenyl)-4-(4-phenyl-pipe...)
Affinity DataKi:  7.80nMAssay Description:Displacement of PPHT-red from SNAP-tagged human D2LR expressed in CHOK1 cell membranes by TR-FRET assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/26/2021
Entry Details Article
PubMed
TargetD(2) dopamine receptor(Human)
University of Nottingham

Curated by ChEMBL
LigandPNGBDBM50019950(CHEMBL56843 | 1-(4-Fluoro-phenyl)-4-(4-phenyl-pipe...)
Affinity DataKi:  7.80nMAssay Description:Displacement of PPHT-red from SNAP-tagged human D2LR expressed in CHOK1 cell membranes by TR-FRET assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/26/2021
Entry Details Article
PubMed