BDBM50019968 7-Ethyl-1,3,5-trimethyl-6,7-dihydro-1H-1,2,4,5a,8-pentaaza-as-indacene::CHEMBL143865

SMILES CCC1CN2C(=N1)c1c(N=C2C)c(C)nn1C

InChI Key InChIKey=YFAVYALYCRERKH-UHFFFAOYSA-N

Data  11 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 11 hits for monomerid = 50019968   

TargetAlpha-1A/Alpha-1B/Alpha-1D adrenergic receptor(Rat)
Warner-Lambert

Curated by ChEMBL
LigandPNGBDBM50019968(CHEMBL143865 | 7-Ethyl-1,3,5-trimethyl-6,7-dihydro...)
Affinity DataIC50: 1.00E+4nMAssay Description:Displacement of [3H]WB-4101 from alpha-1 adrenergic receptor in rat brainMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
LigandPNGBDBM50019968(CHEMBL143865 | 7-Ethyl-1,3,5-trimethyl-6,7-dihydro...)
Affinity DataIC50: 1.00E+4nMAssay Description:Displacement of [3H]clonidine from alpha-2 adrenergic receptor in rat brainMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetD(1A) dopamine receptor(Rat)
Warner-Lambert

Curated by ChEMBL
LigandPNGBDBM50019968(CHEMBL143865 | 7-Ethyl-1,3,5-trimethyl-6,7-dihydro...)
Affinity DataIC50: 1.00E+4nMAssay Description:Displacement of [3H]cis-flupenthixol from Dopamine receptor D1 in rat brainMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetMuscarinic acetylcholine receptor M1/M2/M3/M4/M5(Rat)
Warner-Lambert

Curated by ChEMBL
LigandPNGBDBM50019968(CHEMBL143865 | 7-Ethyl-1,3,5-trimethyl-6,7-dihydro...)
Affinity DataIC50: 1.00E+4nMAssay Description:Displacement of [3H]quinuclidinyl benzilate(QNB) from Muscarinic acetylcholine receptor in rat brainMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetBeta-2 adrenergic receptor(Rat)
Warner-Lambert

Curated by ChEMBL
LigandPNGBDBM50019968(CHEMBL143865 | 7-Ethyl-1,3,5-trimethyl-6,7-dihydro...)
Affinity DataIC50: 1.00E+4nMAssay Description:Displacement of [3H]DHA (Dihydroalprenolol) from beta-2 adrenergic receptor in rat brainMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetBeta-1 adrenergic receptor(Rat)
Warner-Lambert

Curated by ChEMBL
LigandPNGBDBM50019968(CHEMBL143865 | 7-Ethyl-1,3,5-trimethyl-6,7-dihydro...)
Affinity DataIC50: 1.00E+4nMAssay Description:Displacement of [3H]DHA (Dihydroalprenolol) from beta-1 adrenergic receptor in rat brainMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 1A/1B/1D/1F(Rat)
Warner-Lambert

Curated by ChEMBL
LigandPNGBDBM50019968(CHEMBL143865 | 7-Ethyl-1,3,5-trimethyl-6,7-dihydro...)
Affinity DataIC50: 1.00E+4nMAssay Description:Displacement of [3H]5-HT from serotonin-1 neurotransmitter receptor in rat brainMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetSerotonin 2 (5-HT2) receptor(Rat)
Warner-Lambert

Curated by ChEMBL
LigandPNGBDBM50019968(CHEMBL143865 | 7-Ethyl-1,3,5-trimethyl-6,7-dihydro...)
Affinity DataIC50: 1.00E+4nMAssay Description:Displacement of [3H]spiroperidol from 5-hydroxytryptamine 2 receptor in rat brainMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetAdenosine receptor A1(Rat)
Warner-Lambert

Curated by ChEMBL
LigandPNGBDBM50019968(CHEMBL143865 | 7-Ethyl-1,3,5-trimethyl-6,7-dihydro...)
Affinity DataIC50: 1.00E+4nMAssay Description:Displacement of [3H]CHA (N6-Cyclohexyl adenosine) from adenosine A1 receptor in rat brainMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetD(2) dopamine receptor(Rat)
Warner-Lambert

Curated by ChEMBL
LigandPNGBDBM50019968(CHEMBL143865 | 7-Ethyl-1,3,5-trimethyl-6,7-dihydro...)
Affinity DataIC50: 1.00E+4nMAssay Description:Displacement of [3H]haloperidol from Dopamine receptor D2 in rat brainMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
LigandPNGBDBM50019968(CHEMBL143865 | 7-Ethyl-1,3,5-trimethyl-6,7-dihydro...)
Affinity DataIC50: 1.00E+4nMAssay Description:Displacement of [3H]nitrendipine from L-type [Ca2+] channel of rat brainMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed