BDBM50020002 2-{4-[4-(2,4-Dioxo-1-thia-3-aza-spiro[4.4]non-3-yl)-butyl]-piperazin-1-yl}-nicotinonitrile::CHEMBL348150

SMILES O=C1SC2(CCCC2)C(=O)N1CCCCN1CCN(CC1)c1ncccc1C#N

InChI Key InChIKey=BALZWNJGDNTUFK-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50020002   

TargetD(2) dopamine receptor(Rat)
Bristol-Myers

Curated by ChEMBL
LigandPNGBDBM50020002(CHEMBL348150 | 2-{4-[4-(2,4-Dioxo-1-thia-3-aza-spi...)
Affinity DataIC50: 34nMAssay Description:Ability to inhibit [3H]spiperone binding to Dopamine receptor D2 in rat corpus striatumMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetAlpha-1A/Alpha-1B/Alpha-1D adrenergic receptor(Rat)
Bristol-Myers

Curated by ChEMBL
LigandPNGBDBM50020002(CHEMBL348150 | 2-{4-[4-(2,4-Dioxo-1-thia-3-aza-spi...)
Affinity DataIC50: 35nMAssay Description:Ability to inhibit [3H]WB-4101 binding to rat cortical alpha-1-adrenergic receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed