BDBM50020241 1-[6-Fluoro-3-(4-fluoro-phenyl)-indan-1-yl]-4-methyl-piperazine::CHEMBL305905

SMILES CN1CCN(CC1)[C@H]1C[C@@H](c2ccc(F)cc12)c1ccc(F)cc1

InChI Key InChIKey=BOFPIRRSGDHUCZ-UHFFFAOYSA-N

Data  6 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 6 hits for monomerid = 50020241   

TargetTransporter(Rat)
H. Lundbeck

Curated by ChEMBL
LigandPNGBDBM50020241(CHEMBL305905 | 1-[6-Fluoro-3-(4-fluoro-phenyl)-ind...)
Affinity DataIC50: 28nMAssay Description:In vitro inhibition of [3H]norepinephrine uptake in rat brain synaptosomesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/16/2012
Entry Details Article
PubMed
TargetSerotonin 2 (5-HT2) receptor(Rat)
H. Lundbeck

Curated by ChEMBL
LigandPNGBDBM50020241(CHEMBL305905 | 1-[6-Fluoro-3-(4-fluoro-phenyl)-ind...)
Affinity DataIC50: 43nMAssay Description:Inhibition of [3H]spiperone binding to 5-hydroxytryptamine 2 receptor from rat cortical membranesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/16/2012
Entry Details Article
PubMed
TargetSodium-dependent dopamine transporter(Rat)
H. Lundbeck

Curated by ChEMBL
LigandPNGBDBM50020241(CHEMBL305905 | 1-[6-Fluoro-3-(4-fluoro-phenyl)-ind...)
Affinity DataIC50: 81nMAssay Description:In vitro inhibition of [3H]dopamine uptake in rat brain synaptosomesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/16/2012
Entry Details Article
PubMed
LigandPNGBDBM50020241(CHEMBL305905 | 1-[6-Fluoro-3-(4-fluoro-phenyl)-ind...)
Affinity DataIC50: 85nMAssay Description:Inhibition of [3H]prazosin binding to alpha-1 adrenergic receptor from rat cortical membranesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/16/2012
Entry Details Article
PubMed
TargetD(2) dopamine receptor(Rat)
H. Lundbeck

Curated by ChEMBL
LigandPNGBDBM50020241(CHEMBL305905 | 1-[6-Fluoro-3-(4-fluoro-phenyl)-ind...)
Affinity DataIC50: 410nMAssay Description:Inhibition of [3H]spiperone binding to Dopamine receptor D2 from rat striatal membranesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/16/2012
Entry Details Article
PubMed
TargetSodium-dependent serotonin transporter(Rat)
H. Lundbeck

Curated by ChEMBL
LigandPNGBDBM50020241(CHEMBL305905 | 1-[6-Fluoro-3-(4-fluoro-phenyl)-ind...)
Affinity DataIC50: 610nMAssay Description:In vitro inhibition of [3H]5-HT transporter uptake in rat brain synaptosomesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/16/2012
Entry Details Article
PubMed