BDBM50020271 (RS)-[3-[3-(4-Chloro-phenyl)-ureido]-5-(2-fluoro-phenyl)-2-oxo-2,3-dihydro-benzo[e][1,4]diazepin-1-yl]-acetic acid ethyl ester::CHEMBL417521

SMILES CCOC(=O)CN1c2ccccc2C(=NC(NC(=O)Nc2ccc(Cl)cc2)C1=O)c1ccccc1F

InChI Key InChIKey=LEAKDRUEDMNHQD-UHFFFAOYSA-N

Data  5 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 50020271   

TargetGastrin/cholecystokinin type B receptor(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50020271(CHEMBL417521 | (RS)-[3-[3-(4-Chloro-phenyl)-ureido...)
Affinity DataIC50: 1.20nMAssay Description:Inhibition of binding of [125I]-CCK-8 to the cholecystokinin type B receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/26/2012
Entry Details Article
PubMed
TargetGastrin/cholecystokinin type B receptor(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50020271(CHEMBL417521 | (RS)-[3-[3-(4-Chloro-phenyl)-ureido...)
Affinity DataIC50: 1.20nMAssay Description:Displacement of [125 I] CCK-8 from Cholecystokinin type B receptor of guinea pig cerebral cortexMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/17/2012
Entry Details Article
PubMed
TargetGastrin/cholecystokinin type B receptor(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50020271(CHEMBL417521 | (RS)-[3-[3-(4-Chloro-phenyl)-ureido...)
Affinity DataIC50: 4.10nMAssay Description:Displacement of 125 I-gastrin from gastrin receptor of guinea pig gastric glandsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/17/2012
Entry Details Article
PubMed
TargetCholecystokinin receptor type A(Rat)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50020271(CHEMBL417521 | (RS)-[3-[3-(4-Chloro-phenyl)-ureido...)
Affinity DataIC50: 220nMAssay Description:Inhibition of binding of [125I]CCK-8 to cholecystokinin type A receptor in rat pancreatic tissueMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/26/2012
Entry Details Article
PubMed
TargetCholecystokinin receptor type A(Rat)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50020271(CHEMBL417521 | (RS)-[3-[3-(4-Chloro-phenyl)-ureido...)
Affinity DataIC50: 220nMAssay Description:Displacement of [125 I] CCK-8 from Cholecystokinin type A receptor of rat pancreasMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/17/2012
Entry Details Article
PubMed