BDBM50020509 7-Methoxy-1,2,3,4-tetrahydro-naphthalen-2-ylamine::CHEMBL422274

SMILES COc1ccc2CCC(N)Cc2c1

InChI Key InChIKey=ZNWNWWLWFCCREO-UHFFFAOYSA-N

Data  4 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50020509   

TargetD(3) dopamine receptor(Human)
University of Groningen

Curated by ChEMBL
LigandPNGBDBM50020509(CHEMBL422274 | 7-Methoxy-1,2,3,4-tetrahydro-naphth...)
Affinity DataKi:  2.22E+3nMAssay Description:Binding affinity was evaluated by calculating competition for [3H]spiperone binding on Dopamine receptor D3 expressed on CHO K-1 cells.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/2/2012
Entry Details Article
PubMed
TargetD(4) dopamine receptor(Human)
University of Groningen

Curated by ChEMBL
LigandPNGBDBM50020509(CHEMBL422274 | 7-Methoxy-1,2,3,4-tetrahydro-naphth...)
Affinity DataKi: >3.33E+3nMAssay Description:Binding affinity was evaluated by calculating competition for [3H]spiperone binding on Dopamine receptor D4.2 of CHO K-1 cells.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/2/2012
Entry Details Article
PubMed
TargetD(2) dopamine receptor(Human)
University of Groningen

Curated by ChEMBL
LigandPNGBDBM50020509(CHEMBL422274 | 7-Methoxy-1,2,3,4-tetrahydro-naphth...)
Affinity DataKi:  5.83E+3nMAssay Description:Binding affinity was evaluated by calculating competition for [3H]spiperone binding on Dopamine receptor D2L of CHO K-1 cells.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/2/2012
Entry Details Article
PubMed
TargetPhenylethanolamine N-methyltransferase(Bovine)
University of Kansas

Curated by ChEMBL
LigandPNGBDBM50020509(CHEMBL422274 | 7-Methoxy-1,2,3,4-tetrahydro-naphth...)
Affinity DataKi:  2.28E+5nMAssay Description:The compound was tested for In vitro inhibitory activity against Phenylethanolamine N-Methyltransferase (PNMT)More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/17/2012
Entry Details Article
PubMed