BDBM50020511 6-Amino-5,6,7,8-tetrahydro-naphthalen-1-ol::CHEMBL441092

SMILES NC1CCc2c(O)cccc2C1

InChI Key InChIKey=AUBNLLGXUCCYFZ-UHFFFAOYSA-N

Data  4 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50020511   

TargetD(3) dopamine receptor(Human)
University of Groningen

Curated by ChEMBL
LigandPNGBDBM50020511(CHEMBL441092 | 6-Amino-5,6,7,8-tetrahydro-naphthal...)
Affinity DataKi:  343nMAssay Description:Binding affinity was evaluated by calculating competition for [3H]spiperone binding on Dopamine receptor D3 expressed on CHO K-1 cells.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/2/2012
Entry Details Article
PubMed
TargetD(2) dopamine receptor(Human)
University of Groningen

Curated by ChEMBL
LigandPNGBDBM50020511(CHEMBL441092 | 6-Amino-5,6,7,8-tetrahydro-naphthal...)
Affinity DataKi:  1.49E+3nMAssay Description:Binding affinity was evaluated by calculating competition for [3H]spiperone binding on Dopamine receptor D2L of CHO K-1 cells.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/2/2012
Entry Details Article
PubMed
TargetD(4) dopamine receptor(Human)
University of Groningen

Curated by ChEMBL
LigandPNGBDBM50020511(CHEMBL441092 | 6-Amino-5,6,7,8-tetrahydro-naphthal...)
Affinity DataKi: >3.33E+3nMAssay Description:Binding affinity was evaluated by calculating competition for [3H]spiperone binding on Dopamine receptor D4.2 of CHO K-1 cells.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/2/2012
Entry Details Article
PubMed
TargetPhenylethanolamine N-methyltransferase(Bovine)
University of Kansas

Curated by ChEMBL
LigandPNGBDBM50020511(CHEMBL441092 | 6-Amino-5,6,7,8-tetrahydro-naphthal...)
Affinity DataKi:  2.10E+4nMAssay Description:The compound was tested for In vitro inhibitory activity against Phenylethanolamine N-Methyltransferase (PNMT)More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/17/2012
Entry Details Article
PubMed