BDBM50020583 CHEMBL3290439

SMILES COc1cc(\C=C\C(=O)CC(=O)c2ccc(O)c(OC)c2)ccc1O

InChI Key InChIKey=WGRFGQJWSXSKER-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50020583   

TargetPolyunsaturated fatty acid 5-lipoxygenase(Human)
University Jena

Curated by ChEMBL
LigandPNGBDBM50020583(CHEMBL3290439)
Affinity DataIC50: 2.30E+3nMAssay Description:Inhibition of human recombinant 5-LO expressed in Escherichia coli Bl21 (DE3) using arachidonic acid as substrate preincubated for 10 mins measured a...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/11/2015
Entry Details Article
PubMed
TargetPolyunsaturated fatty acid 5-lipoxygenase(Human)
University Jena

Curated by ChEMBL
LigandPNGBDBM50020583(CHEMBL3290439)
Affinity DataIC50: 9.90E+3nMAssay Description:Inhibition of 5-LO in human neutrophils using arachidonic acid as substrate preincubated for 15 mins measured after 10 mins by HPLC analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/11/2015
Entry Details Article
PubMed
TargetSignal transducer and activator of transcription 3(Human)
University Jena

Curated by ChEMBL
LigandPNGBDBM50020583(CHEMBL3290439)
Affinity DataIC50: 3.57E+4nMAssay Description:Inhibition of STAT3 transcriptional activity in human HaCaT cells after 6 hrs by luciferase reporter gene assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/11/2015
Entry Details Article
PubMed