BDBM50020727 CHEMBL3291220

SMILES Cc1[nH]c(c(c1-c1ccnc2c(cnn12)C#N)-c1ccccc1)-c1ccccc1

InChI Key InChIKey=MXIJUGWISQCVAH-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50020727   

TargetE3 ubiquitin-protein ligase Mdm2(Human)
Cairo University

Curated by ChEMBL
LigandPNGBDBM50020727(CHEMBL3291220)
Affinity DataIC50: 910nMAssay Description:Inhibition of GST-tagged HDM2 (unknown origin) expressed in Escherichia coli BL21 cells assessed as p53 activation by measuring inhibition of His-p53...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/11/2015
Entry Details Article
PubMed