BDBM50021546 4-Fluoro-3-(1-hydroxy-2-methylamino-ethyl)-phenol::4-Fluoro-3-(1-hydroxy-2-methylamino-ethyl)-phenol(6-FPE)::CHEMBL61372

SMILES CNCC(O)c1cc(O)ccc1F

InChI Key InChIKey=YTBMWHRBVZXATF-UHFFFAOYSA-N

Data  4 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50021546   

LigandPNGBDBM50021546(CHEMBL61372 | 4-Fluoro-3-(1-hydroxy-2-methylamino-...)
Affinity DataKi:  230nMAssay Description:Compound was tested for its ability to displace [3H]clonidine form alpha-2 adrenergic receptor site in guinea pig cerebral cortical membranes.More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/17/2018
Entry Details Article
PubMed
TargetAlpha-2A adrenergic receptor [16-465]/Alpha-2B adrenergic receptor/Alpha-2C adrenergic receptor(Rat)
National Institute of Diabetes and Digestive and Kidney Diseases

Curated by ChEMBL
LigandPNGBDBM50021546(CHEMBL61372 | 4-Fluoro-3-(1-hydroxy-2-methylamino-...)
Affinity DataKi:  230nMAssay Description:Displacement of [3H]clonidine from adrenergic alpha 2 receptor of rat cerebral cortical membranesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/26/2012
Entry Details Article
PubMed
TargetAlpha-1A/Alpha-1B/Alpha-1D adrenergic receptor(Rat)
National Institute of Diabetes and Digestive and Kidney Diseases

Curated by ChEMBL
LigandPNGBDBM50021546(CHEMBL61372 | 4-Fluoro-3-(1-hydroxy-2-methylamino-...)
Affinity DataKi:  2.10E+3nMAssay Description:Displacement of [3H]WB-4101 from adrenergic alpha 1 receptor of rat cerebral cortical membranesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/26/2012
Entry Details Article
PubMed
TargetBeta-1 adrenergic receptor(Rat)
National Institute of Diabetes and Digestive and Kidney Diseases

Curated by ChEMBL
LigandPNGBDBM50021546(CHEMBL61372 | 4-Fluoro-3-(1-hydroxy-2-methylamino-...)
Affinity DataKi:  1.80E+5nMAssay Description:Displacement of [3H]dihydroalprenolol from adrenergic beta 1 receptor of rat cerebral cortical membranesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/26/2012
Entry Details Article
PubMed