BDBM50021738 CHEMBL3297857

SMILES CC(C)Nc1ncc2CCN(Cc2n1)C(=O)N[C@H](CNCCO)c1ccc(F)c(Cl)c1

InChI Key InChIKey=XMLADQRYVGCROP-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50021738   

TargetMitogen-activated protein kinase 1(Human)
Array Biopharma

Curated by ChEMBL
LigandPNGBDBM50021738(CHEMBL3297857)
Affinity DataIC50: 8nMAssay Description:Inhibition of human recombinant N-terminal 6-His-tagged ERK2 expressed in Escherichia coli using S/T17 as substrate after 30 mins by spectrophotometr...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/12/2015
Entry Details Article
PubMed
TargetMitogen-activated protein kinase 1(Human)
Array Biopharma

Curated by ChEMBL
LigandPNGBDBM50021738(CHEMBL3297857)
Affinity DataIC50: 2.76E+3nMAssay Description:Inhibition of ERK2 in human HepG2 cells assessed as P90RSK phosphorylation at Ser380 after 1.5 hrs by fluorescence assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/12/2015
Entry Details Article
PubMed