BDBM50022033 CHEMBL418305::{1-[1-{3-[1-(3-Aminomethyl-benzylcarbamoyl)-3-methyl-butylcarbamoyl]-1-cyclohexylmethyl-2-hydroxy-propylcarbamoyl}-2-(1H-imidazol-4-yl)-ethylcarbamoyl]-2-phenyl-ethyl}-carbamic acid tert-butyl ester

SMILES CC(C)C[C@H](NC(=O)CC(O)C(CC1CCCCC1)NC(=O)[C@H](Cc1cnc[nH]1)NC(=O)[C@H](Cc1ccccc1)NC(=O)OC(C)(C)C)C(=O)NCc1cccc(CN)c1

InChI Key InChIKey=QIGZLJVYYYXMIH-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50022033   

TargetRenin(Human)
Merck Sharp & Dohme Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50022033({1-[1-{3-[1-(3-Aminomethyl-benzylcarbamoyl)-3-meth...)
Affinity DataIC50: 8.30nMAssay Description:Inhibition of porcine kidney reninMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetRenin(Human)
Merck Sharp & Dohme Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50022033({1-[1-{3-[1-(3-Aminomethyl-benzylcarbamoyl)-3-meth...)
Affinity DataIC50: 1nMAssay Description:Concentration required for 50% inhibition of human plasma reninMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetRenin(Human)
Merck Sharp & Dohme Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50022033({1-[1-{3-[1-(3-Aminomethyl-benzylcarbamoyl)-3-meth...)
Affinity DataIC50: 3.30nMAssay Description:Inhibition of reninMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed