BDBM50022281 2-{4-[(2-Amino-4-hydroxy-pteridin-6-ylmethyl)-methyl-amino]-benzoylamino}-pentanedioic acid::CHEMBL276968

SMILES CN(Cc1cnc2nc(N)[nH]c(=O)c2n1)c1ccc(cc1)C(=O)NC(CCC(O)=O)C(O)=O

InChI Key InChIKey=HLIXOCXUWGDBNP-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50022281   

TargetThymidylate synthase(Mouse)
TBA

Curated by ChEMBL
LigandPNGBDBM50022281(2-{4-[(2-Amino-4-hydroxy-pteridin-6-ylmethyl)-meth...)
Affinity DataIC50: 6.60E+5nMAssay Description:Inhibitory activity against thymidylate synthase in the intact L1210 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/14/2012
Entry Details Article
PubMed
TargetThymidylate synthase(Mouse)
TBA

Curated by ChEMBL
LigandPNGBDBM50022281(2-{4-[(2-Amino-4-hydroxy-pteridin-6-ylmethyl)-meth...)
Affinity DataIC50: 1.00E+6nMAssay Description:Inhibitory activity against thymidylate synthase in the intact L1210 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/14/2012
Entry Details Article
PubMed