BDBM50022945 CHEMBL3143679::{1-[1-[(1S,2R,3R,4R)-2,3-Dihydroxy-1-isobutyl-5-methyl-4-((S)-2-methyl-butylcarbamoyl)-hexylcarbamoyl]-2-(1H-imidazol-4-yl)-ethylcarbamoyl]-2-phenyl-ethyl}-carbamic acid tert-butyl ester

SMILES CC[C@H](C)CNC(=O)[C@H](C(C)C)[C@@H](O)[C@H](O)[C@H](CC(C)C)NC(=O)[C@H](Cc1c[nH]cn1)NC(=O)[C@H](Cc1ccccc1)NC(=O)OC(C)(C)C

InChI Key InChIKey=PIKMEJCYGLUULJ-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50022945   

TargetRenin(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50022945({1-[1-[(1S,2R,3R,4R)-2,3-Dihydroxy-1-isobutyl-5-me...)
Affinity DataIC50: 3.40E+3nMAssay Description:Tested for the inhibition of human plasma reninMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed