BDBM50023131 CHEMBL3298940

SMILES OC(=O)C[C@H](NC(=O)C1(CS)CCCC1)C(O)=O

InChI Key InChIKey=VYDZHYRRODGVRG-UHFFFAOYSA-N

Data  3 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50023131   

TargetNeprilysin(Human)
Pharmaleads

Curated by ChEMBL
LigandPNGBDBM50023131(CHEMBL3298940)
Affinity DataKi:  3.40nMAssay Description:Inhibition of recombinant human Neprilysin using Suc-Ala-Ala-Phe-AMC as substrate preincubated for 30 mins followed by substrate addition measured af...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/13/2016
Entry Details Article
PubMed
TargetNeprilysin(Human)
Pharmaleads

Curated by ChEMBL
LigandPNGBDBM50023131(CHEMBL3298940)
Affinity DataKi:  3.5nMAssay Description:Inhibition of human recombinant NEP using Suc-Ala-Ala-Phe-AMC as substrate after 30 mins by fluorimetryMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/12/2015
Entry Details Article
PubMed
TargetAminopeptidase N(Human)
Pharmaleads

Curated by ChEMBL
LigandPNGBDBM50023131(CHEMBL3298940)
Affinity DataKi: >1.00E+4nMAssay Description:Inhibition of recombinant human Aminopeptidase N using L-Ala-beta-NA as substrate preincubated for 30 mins followed by substrate addition measured af...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/13/2016
Entry Details Article
PubMed