BDBM50023492 5-Amino-2-furan-2-yl-[1,2,4]triazolo[1,5-c]quinazolin-9-ol::CHEMBL268550

SMILES Nc1nc2ccc(O)cc2c2nc(nn12)-c1ccco1

InChI Key InChIKey=WQGNZMYSKIBCKI-UHFFFAOYSA-N

Data  5 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 50023492   

TargetAdenosine receptor A1(Rat)
Ciba-Geigy

Curated by ChEMBL
LigandPNGBDBM50023492(5-Amino-2-furan-2-yl-[1,2,4]triazolo[1,5-c]quinazo...)
Affinity DataIC50: 9.5nMAssay Description:Inhibition of binding towards adenosine A1 receptor using [3H]N-cyclohexyladenosine ([3H]CHA) in rat whole brain membranes.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetAdenosine receptor A2a/A2b(Rat)
Ciba-Geigy

Curated by ChEMBL
LigandPNGBDBM50023492(5-Amino-2-furan-2-yl-[1,2,4]triazolo[1,5-c]quinazo...)
Affinity DataIC50: 5.5nMAssay Description:Inhibition of binding to Adenosine-2 receptor using [3H]NECA in rat striatumMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetCasein kinase I isoform delta(Human)
Technical University Dortmund

Curated by ChEMBL
LigandPNGBDBM50023492(5-Amino-2-furan-2-yl-[1,2,4]triazolo[1,5-c]quinazo...)
Affinity DataIC50: 3.64E+3nMAssay Description:Inhibition of CK1delta (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/18/2023
Entry Details
PubMed
TargetCasein kinase I isoform epsilon(Human)
Technical University Dortmund

Curated by ChEMBL
LigandPNGBDBM50023492(5-Amino-2-furan-2-yl-[1,2,4]triazolo[1,5-c]quinazo...)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of CK1epsilon (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/18/2023
Entry Details
PubMed
TargetCasein kinase I isoform alpha(Human)
Technical University Dortmund

Curated by ChEMBL
LigandPNGBDBM50023492(5-Amino-2-furan-2-yl-[1,2,4]triazolo[1,5-c]quinazo...)
Affinity DataIC50: 6.18E+3nMAssay Description:Inhibition of CK1alpha (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/18/2023
Entry Details
PubMed