BDBM50023721 5-(4-Chloro-benzoylamino)-2-{4-[(2,4-diamino-pteridin-6-ylmethyl)-formyl-amino]-benzoylamino}-pentanoic acid::CHEMBL283702

SMILES Nc1nc(N)c2nc(CN(C=O)c3ccc(cc3)C(=O)NC(CCCNC(=O)c3ccc(Cl)cc3)C(O)=O)cnc2n1

InChI Key InChIKey=XVKWCKAUCRQXJE-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50023721   

TargetDihydrofolate reductase(Mouse)
Harvard Medical School

Curated by ChEMBL
LigandPNGBDBM50023721(5-(4-Chloro-benzoylamino)-2-{4-[(2,4-diamino-pteri...)
Affinity DataIC50: 15nMAssay Description:Inhibition of dihydrofolate reductase (DHFR) from murine leukemia cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/16/2012
Entry Details Article
PubMed