BDBM50024972 (+) 6-[2-(3,5-Dichloro-4''-fluoro-biphenyl-2-yl)-vinyl]-4-hydroxy-tetrahydro-pyran-2-one::(-) 6-[2-(3,5-Dichloro-4''-fluoro-biphenyl-2-yl)-vinyl]-4-hydroxy-tetrahydro-pyran-2-one::6-[2-(3,5-Dichloro-4''-fluoro-biphenyl-2-yl)-vinyl]-4-hydroxy-tetrahydro-pyran-2-one::CHEMBL2368970

SMILES O[C@@H]1C[C@H](OC(=O)C1)\C=C\c1c(Cl)cc(Cl)cc1-c1ccc(F)cc1

InChI Key InChIKey=VMMVXGKAALDTIC-UHFFFAOYSA-N

Data  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50024972   

LigandPNGBDBM50024972(6-[2-(3,5-Dichloro-4''-fluoro-biphenyl-2-yl)-vinyl...)
Affinity DataIC50: 5nMAssay Description:Inhibition of solubilized partially purified rat liver HMG-CoA reductaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
LigandPNGBDBM50024972(6-[2-(3,5-Dichloro-4''-fluoro-biphenyl-2-yl)-vinyl...)
Affinity DataIC50: 5nMAssay Description:Inhibition of solubilized partially purified rat liver HMG-CoA reductaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
LigandPNGBDBM50024972(6-[2-(3,5-Dichloro-4''-fluoro-biphenyl-2-yl)-vinyl...)
Affinity DataIC50: 24nMAssay Description:Compound was tested in vitro for its ability to inhibit rat liver HMG-CoA reductaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
LigandPNGBDBM50024972(6-[2-(3,5-Dichloro-4''-fluoro-biphenyl-2-yl)-vinyl...)
Affinity DataIC50: 260nMAssay Description:Inhibition of solubilized partially purified rat liver HMG-CoA reductaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed