BDBM50026734 CHEMBL3331508

SMILES Clc1ccccc1CN(CC1CNC1)c1ccccc1

InChI Key InChIKey=DXNPAVQXOHJRHQ-UHFFFAOYSA-N

Data  8 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 8 hits for monomerid = 50026734   

TargetSodium-dependent serotonin transporter(Human)
Korea University

Curated by ChEMBL
LigandPNGBDBM50026734(CHEMBL3331508)
Affinity DataIC50: 1.60nMAssay Description:Inhibition of human NET expressed in HEK293 cells at incubated for 15 mins by neurotransmitter reuptake assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/7/2016
Entry Details Article
PubMed
TargetSodium-dependent serotonin transporter(Human)
Korea University

Curated by ChEMBL
LigandPNGBDBM50026734(CHEMBL3331508)
Affinity DataIC50: 5.20nMAssay Description:Inhibition of human SERT expressed in HEK293 cells at incubated for 15 mins by neurotransmitter reuptake assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/7/2016
Entry Details Article
PubMed
TargetCytochrome P450 3A4(Human)
Korea University

Curated by ChEMBL
LigandPNGBDBM50026734(CHEMBL3331508)
Affinity DataIC50: 120nMAssay Description:Inhibition of human recombinant CYP3A4 incubated for 5 mins by fluorescence assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/7/2016
Entry Details Article
PubMed
TargetCytochrome P450 2C9(Human)
Korea University

Curated by ChEMBL
LigandPNGBDBM50026734(CHEMBL3331508)
Affinity DataIC50: 360nMAssay Description:Inhibition of human recombinant CYP2C9 incubated for 5 mins by fluorescence assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/7/2016
Entry Details Article
PubMed
TargetSodium-dependent dopamine transporter(Human)
Korea University

Curated by ChEMBL
LigandPNGBDBM50026734(CHEMBL3331508)
Affinity DataIC50: 441nMAssay Description:Inhibition of human DAT expressed in HEK293 cells at incubated for 15 mins by neurotransmitter reuptake assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/7/2016
Entry Details Article
PubMed
TargetCytochrome P450 2D6(Human)
Korea University

Curated by ChEMBL
LigandPNGBDBM50026734(CHEMBL3331508)
Affinity DataIC50: 1.88E+3nMAssay Description:Inhibition of human recombinant CYP2D6 incubated for 5 mins by fluorescence assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/7/2016
Entry Details Article
PubMed
TargetCytochrome P450 2C19(Human)
Korea University

Curated by ChEMBL
LigandPNGBDBM50026734(CHEMBL3331508)
Affinity DataIC50: 5.40E+3nMAssay Description:Inhibition of human recombinant CYP2C19 incubated for 5 mins by fluorescence assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/7/2016
Entry Details Article
PubMed
TargetCytochrome P450 1A2(Human)
Korea University

Curated by ChEMBL
LigandPNGBDBM50026734(CHEMBL3331508)
Affinity DataIC50: 5.27E+4nMAssay Description:Inhibition of human recombinant CYP1A2 incubated for 5 mins by fluorescence assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/7/2016
Entry Details Article
PubMed