BDBM50026847 1-[2-(6,7-Dimethoxy-isochroman-1-yl)-ethyl]-4-(4-fluoro-phenyl)-piperazine::CHEMBL83915

SMILES COc1cc2CCOC(CCN3CCN(CC3)c3ccc(F)cc3)c2cc1OC

InChI Key InChIKey=PAHAVOZGHBZJNZ-UHFFFAOYSA-N

Data  6 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 6 hits for monomerid = 50026847   

LigandPNGBDBM50026847(1-[2-(6,7-Dimethoxy-isochroman-1-yl)-ethyl]-4-(4-f...)
Affinity DataKi:  4nMAssay Description:Compound was tested for the inhibition of [3H]prazosin binding alpha-1-adrenergic receptor of crude rat brain membrane.More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/4/2018
Entry Details Article
PubMed
TargetD(4) dopamine receptor(Rat)
Pharmacia & Upjohn

Curated by ChEMBL
LigandPNGBDBM50026847(1-[2-(6,7-Dimethoxy-isochroman-1-yl)-ethyl]-4-(4-f...)
Affinity DataKi:  24nMAssay Description:Binding affinity of [3H]spiperone towards Dopamine receptor D4 expressed in cultured cells or from rat whole brain.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetD(1A) dopamine receptor(Rat)
Pharmacia & Upjohn

Curated by ChEMBL
LigandPNGBDBM50026847(1-[2-(6,7-Dimethoxy-isochroman-1-yl)-ethyl]-4-(4-f...)
Affinity DataKi:  26nMAssay Description:Binding affinity of [3H]SCH-23,390 towards Dopamine receptor D1 in cloned mammalian receptor expressed in cultured cells or from rat whole brain.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
LigandPNGBDBM50026847(1-[2-(6,7-Dimethoxy-isochroman-1-yl)-ethyl]-4-(4-f...)
Affinity DataKi:  62nMAssay Description:Compound was tested for the inhibition of [3H]clonidine binding Alpha-2 adrenergic receptor of crude rat brain membraneMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/4/2018
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 1A(Rat)
Pharmacia & Upjohn

Curated by ChEMBL
LigandPNGBDBM50026847(1-[2-(6,7-Dimethoxy-isochroman-1-yl)-ethyl]-4-(4-f...)
Affinity DataKi:  93nMAssay Description:Binding affinity of [3H]-8-OH-DPAT towards 5-hydroxytryptamine 1A receptor in cloned mammalian receptor expressed in cultured cells or from rat whole...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetD(2) dopamine receptor(Rat)
Pharmacia & Upjohn

Curated by ChEMBL
LigandPNGBDBM50026847(1-[2-(6,7-Dimethoxy-isochroman-1-yl)-ethyl]-4-(4-f...)
Affinity DataKi:  400nMAssay Description:Binding affinity of [3H]U-86170 towards Dopamine receptor D2 in cloned mammalian receptor expressed in cultured cells or from rat whole brainMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed