BDBM50027482 CHEMBL1256531::US11866416, Compound SN-II-32

SMILES Oc1ccc(\C=C\C(=O)c2ccccc2O)c(O)c1

InChI Key InChIKey=ZLEFYDUXMWKPSH-UHFFFAOYSA-N

Data  2 IC50  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50027482   

TargetPolyphenol oxidase 2(White button mushroom)
Jiangnan University

Curated by ChEMBL
LigandPNGBDBM50027482(CHEMBL1256531 | US11866416, Compound SN-II-32)
Affinity DataIC50: 29nMAssay Description:Inhibition of mushroom tyrosinase using L-tyrosine as substrate after 20 mins by spectrophotometric methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/5/2017
Entry Details Article
PubMed
TargetNeuronal acetylcholine receptor subunit alpha-7(Human)
Instituto De Qu£Mica M£Dica (Iqm-Csic)

Curated by ChEMBL
LigandPNGBDBM50027482(CHEMBL1256531 | US11866416, Compound SN-II-32)
Affinity DataEC50:  3.45E+4nMAssay Description:Positive allosteric modulation at human alpha7 nACHR expressed in Xenopus oocyte assessed as potentiation of 200 uM ACh-induced current at holding po...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/8/2016
Entry Details Article
PubMed
TargetBiofilm regulatory protein A(Streptococcus mutans serotype c (strain ATCC 70061...)
Uab Research Foundation

US Patent
LigandPNGBDBM50027482(CHEMBL1256531 | US11866416, Compound SN-II-32)
Affinity DataIC50: 2.50E+5nMAssay Description:A previously reported zymographic assay was utilized for the investigation of Gtf enzymatic activity, as described in Example 1. A 1:100 in fresh 5 m...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/2/2024
Entry Details
US Patent