BDBM50028083 CHEMBL37714::[4-(4-Chloro-phenyl)-1,2,3,4-tetrahydro-naphthalen-1-yl]-methyl-amine::[4-(4-Chloro-phenyl)-1,2,3,4-tetrahydro-naphthalen-1-yl]-methyl-amine, HCl

SMILES CN[C@@H]1CC[C@@H](c2ccc(Cl)cc2)c2ccccc12

InChI Key InChIKey=LLMOMOOMHWFGRN-UHFFFAOYSA-N

Data  6 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 6 hits for monomerid = 50028083   

TargetTransporter(Rat)
TBA

Curated by ChEMBL
LigandPNGBDBM50028083([4-(4-Chloro-phenyl)-1,2,3,4-tetrahydro-naphthalen...)
Affinity DataIC50: 19nMAssay Description:Inhibition of norepinephrine uptake in synaptosomal preparation fro rat hypothalamus, using [3H]norepinephrineMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/13/2012
Entry Details Article
PubMed
LigandPNGBDBM50028083([4-(4-Chloro-phenyl)-1,2,3,4-tetrahydro-naphthalen...)
Affinity DataIC50: 52nMAssay Description:Inhibition of dopamine uptake in synaptosomal preparation in rat corpus striatum, using [3H]dopamineMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/13/2012
Entry Details Article
PubMed
LigandPNGBDBM50028083([4-(4-Chloro-phenyl)-1,2,3,4-tetrahydro-naphthalen...)
Affinity DataIC50: 84nMAssay Description:Inhibition of 5-HT uptake in synaptosomal preparation from rat corpus striatum, using [3H]5-HTMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/13/2012
Entry Details Article
PubMed
TargetTransporter(Rat)
TBA

Curated by ChEMBL
LigandPNGBDBM50028083([4-(4-Chloro-phenyl)-1,2,3,4-tetrahydro-naphthalen...)
Affinity DataIC50: 460nMAssay Description:Inhibition of norepinephrine uptake in synaptosomal preparation fro rat hypothalamus, using [3H]norepinephrineMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/13/2012
Entry Details Article
PubMed
LigandPNGBDBM50028083([4-(4-Chloro-phenyl)-1,2,3,4-tetrahydro-naphthalen...)
Affinity DataIC50: 1.40E+3nMAssay Description:Inhibition of dopamine uptake in synaptosomal preparation in rat corpus striatum, using [3H]dopamineMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/13/2012
Entry Details Article
PubMed
LigandPNGBDBM50028083([4-(4-Chloro-phenyl)-1,2,3,4-tetrahydro-naphthalen...)
Affinity DataIC50: 3.50E+3nMAssay Description:Inhibition of 5-HT uptake in synaptosomal preparation from rat corpus striatum, using [3H]5-HTMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/13/2012
Entry Details Article
PubMed