BDBM50028093 CHEMBL39405::Dimethyl-[4-(3-trifluoromethyl-phenyl)-1,2,3,4-tetrahydro-naphthalen-1-yl]-amine, C4H4O4

SMILES CN(C)[C@H]1CC[C@@H](c2cccc(c2)C(F)(F)F)c2ccccc12

InChI Key InChIKey=MKSRSZKGUKRVLK-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50028093   

LigandPNGBDBM50028093(Dimethyl-[4-(3-trifluoromethyl-phenyl)-1,2,3,4-tet...)
Affinity DataIC50: 190nMAssay Description:Inhibition of 5-HT uptake in synaptosomal preparation from rat corpus striatum, using [3H]5-HTMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/13/2012
Entry Details Article
PubMed
TargetTransporter(Rat)
TBA

Curated by ChEMBL
LigandPNGBDBM50028093(Dimethyl-[4-(3-trifluoromethyl-phenyl)-1,2,3,4-tet...)
Affinity DataIC50: 890nMAssay Description:Inhibition of norepinephrine uptake in synaptosomal preparation fro rat hypothalamus, using [3H]norepinephrineMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/13/2012
Entry Details Article
PubMed
LigandPNGBDBM50028093(Dimethyl-[4-(3-trifluoromethyl-phenyl)-1,2,3,4-tet...)
Affinity DataIC50: 7.00E+3nMAssay Description:Inhibition of dopamine uptake in synaptosomal preparation in rat corpus striatum, using [3H]dopamineMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/13/2012
Entry Details Article
PubMed