BDBM50028281 6-(3,4-Dimethoxy-phenyl)-1,2,3,5,6,10b-hexahydro-pyrrolo[2,1-a]isoquinoline; hydrobromide::CHEMBL556545

SMILES COc1ccc(cc1OC)C1CN2CCC[C@H]2c2ccccc12

InChI Key InChIKey=VTLSINSRSAYCHC-UHFFFAOYSA-N

Data  3 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50028281   

TargetTransporter(Rat)
TBA

Curated by ChEMBL
LigandPNGBDBM50028281(6-(3,4-Dimethoxy-phenyl)-1,2,3,5,6,10b-hexahydro-p...)
Affinity DataKi:  3.40nMAssay Description:Inhibition of norepinephrine (NE) into rat brain synaptosomesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/13/2012
Entry Details Article
PubMed
LigandPNGBDBM50028281(6-(3,4-Dimethoxy-phenyl)-1,2,3,5,6,10b-hexahydro-p...)
Affinity DataKi:  18nMAssay Description:Inhibition of serotonin (5-HT) uptake into rat brain synaptosomesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/13/2012
Entry Details Article
PubMed
LigandPNGBDBM50028281(6-(3,4-Dimethoxy-phenyl)-1,2,3,5,6,10b-hexahydro-p...)
Affinity DataKi:  72nMAssay Description:Inhibition of dopamine (DA) uptake into rat brain synaptosomesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/13/2012
Entry Details Article
PubMed