BDBM50028445 CHEMBL3355112

SMILES C[C@H]1N2C(COc3cc(c(NC4(C)CNC4)cc23)C(F)(F)F)=NNC1=O

InChI Key InChIKey=OUZPGLCFBNPQPF-UHFFFAOYSA-N

Data  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50028445   

TargetProtein kinase C theta type(Human)
Abbvie Bioresearch Center

Curated by ChEMBL
LigandPNGBDBM50028445(CHEMBL3355112)
Affinity DataIC50: 23nMAssay Description:Inhibition of human recombinant PKCtheta expressed in Sf21 cells using Bio-cdc peptide substrate and ATP after 60 mins by time-resolved fluorescence ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/9/2016
Entry Details Article
PubMed
TargetProtein kinase C theta type(Human)
Abbvie Bioresearch Center

Curated by ChEMBL
LigandPNGBDBM50028445(CHEMBL3355112)
Affinity DataIC50: 23nMAssay Description:Inhibition of human recombinant PKCtheta expressed in Sf21 cells using Bio-cdc peptide substrate and ATP after 60 mins by time-resolved fluorescence ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/25/2016
Entry Details Article
PubMed
TargetPotassium voltage-gated channel subfamily H member 2(Human)
Abbvie Bioresearch Center

Curated by ChEMBL
LigandPNGBDBM50028445(CHEMBL3355112)
Affinity DataIC50: 3.00E+4nMAssay Description:Inhibition of human ERGMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/25/2016
Entry Details Article
PubMed
TargetProtein kinase C alpha type(Human)
Abbvie Bioresearch Center

Curated by ChEMBL
LigandPNGBDBM50028445(CHEMBL3355112)
Affinity DataIC50: 1.70E+3nMAssay Description:Inhibition of human recombinant PKCalpha expressed in Sf21 cells using Bio-cdc peptide substrate and ATP after 60 mins by time-resolved fluorescence ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/25/2016
Entry Details Article
PubMed