BDBM50029460 3-{3-[3-(5-Ethyl-4'-fluoro-2-hydroxy-biphenyl-4-yloxy)-propoxy]-9-oxo-9H-xanthen-4-yl}-propionic acid::CHEMBL129463

SMILES CCc1cc(c(O)cc1OCCCOc1ccc2c(oc3ccccc3c2=O)c1CCC(O)=O)-c1ccc(F)cc1

InChI Key InChIKey=AGHWHQVSFVVCAO-UHFFFAOYSA-N

Data  2 KI  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50029460   

TargetLeukotriene B4 receptor 1/2(Human)
Eli Lilly

Curated by ChEMBL
LigandPNGBDBM50029460(3-{3-[3-(5-Ethyl-4'-fluoro-2-hydroxy-biphenyl-4-yl...)
Affinity DataIC50: 1.80nMAssay Description:Inhibition of LTB4-induced up-regulation of human neutrophil CD11b/CD18 integrinMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetLeukotriene B4 receptor 1(Human)
Eli Lilly

Curated by ChEMBL
LigandPNGBDBM50029460(3-{3-[3-(5-Ethyl-4'-fluoro-2-hydroxy-biphenyl-4-yl...)
Affinity DataKi:  36nMAssay Description:Tested for inhibition of specific binding of [3H]LTB4 to human neutrophil expressing LTB4 receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetLeukotriene B4 receptor 1(Human)
Eli Lilly

Curated by ChEMBL
LigandPNGBDBM50029460(3-{3-[3-(5-Ethyl-4'-fluoro-2-hydroxy-biphenyl-4-yl...)
Affinity DataKi:  36nMAssay Description:Tested for inhibition of specific binding of [3H]LTB4 to human neutrophil expressing LTB4 receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed