BDBM50029477 5-(2-Carboxy-ethyl)-6-[3-(5-ethyl-2-hydroxy-biphenyl-4-yloxy)-propoxy]-9-oxo-9H-xanthene-2-carboxylic acid::CHEMBL340460

SMILES CCc1cc(c(O)cc1OCCCOc1ccc2c(oc3ccc(cc3c2=O)C(O)=O)c1CCC(O)=O)-c1ccccc1

InChI Key InChIKey=TXYLRORBUIPAMD-UHFFFAOYSA-N

Data  2 KI  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50029477   

TargetLeukotriene B4 receptor 1/2(Human)
Eli Lilly

Curated by ChEMBL
LigandPNGBDBM50029477(5-(2-Carboxy-ethyl)-6-[3-(5-ethyl-2-hydroxy-biphen...)
Affinity DataIC50: 3.40nMAssay Description:Inhibition of LTB4-induced up-regulation of human neutrophil CD11b/CD18 integrinMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetLeukotriene B4 receptor 1(Human)
Eli Lilly

Curated by ChEMBL
LigandPNGBDBM50029477(5-(2-Carboxy-ethyl)-6-[3-(5-ethyl-2-hydroxy-biphen...)
Affinity DataKi:  0.110nMAssay Description:Tested for inhibition of specific binding of [3H]LTB4 to guinea pig lung membranes expressing LTB4 receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetLeukotriene B4 receptor 1(Human)
Eli Lilly

Curated by ChEMBL
LigandPNGBDBM50029477(5-(2-Carboxy-ethyl)-6-[3-(5-ethyl-2-hydroxy-biphen...)
Affinity DataKi:  0.570nMAssay Description:Tested for inhibition of specific binding of [3H]LTB4 to human neutrophil expressing LTB4 receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed