BDBM50029567 2-[1-(4-Chloro-benzyl)-4-methyl-6-(pyridin-2-ylmethoxy)-4,5-dihydro-1H-thiopyrano[2,3,4-cd]indol-2-ylmethylsulfanyl]-benzoic acid::CHEMBL138551

SMILES CC1Cc2c(OCc3ccccn3)ccc3n(Cc4ccc(Cl)cc4)c(CSc4ccccc4C(O)=O)c(S1)c23

InChI Key InChIKey=UEWUUNANMOHXIH-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50029567   

TargetArachidonate 5-lipoxygenase-activating protein(Human)
Merck Frosst Centre For Therapeutic Research

Curated by ChEMBL
LigandPNGBDBM50029567(2-[1-(4-Chloro-benzyl)-4-methyl-6-(pyridin-2-ylmet...)
Affinity DataIC50: 760nMAssay Description:Inhibition of 5-lipoxygenase activating protein using human leukocyte membrane preparationsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetPolyunsaturated fatty acid 5-lipoxygenase(Human)
Merck Frosst Centre For Therapeutic Research

Curated by ChEMBL
LigandPNGBDBM50029567(2-[1-(4-Chloro-benzyl)-4-methyl-6-(pyridin-2-ylmet...)
Affinity DataIC50: 55nMAssay Description:Inhibition of Human 5-lipoxygenaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed